There are a lot of reasons behind a person's decision to move. Whatever that reason is, you are about to face a new chapter in your life. So, deal with it. If you have a home based business, moving can be a great disturbance. But if you know how organize an appropriate plan, the disruption can be lessen.
Whether you are a business owner or worker, one of the first things that you need to do is to notify your customers and clients about your move. Let them know how long you will be gone or how long it will take to get back to business. If your customers rely on your service or products to complete an important task, make sure you find alternatives for them so they won't feel neglected while you are away.
 Your downtime is entirely up to you. If you make and sell your products, you can continue taking orders till the day before you leave. You can start immediately after you arrive in your destination. However, if more raw materials are needed for your business, start packing your stock 3 to 5 days before your moving day.
However, it will be a different procedure if you work in an external company like a virtual call center or a medical billing company. You need to book you leave ahead of time so others can cover up for your hours. If you are entitled to paid vacations, you can take a longer time-off.
Planning you move will be a careful balance of organization, safety and the needs of your customers. With proper notifications and organized planning, the disruption can be manageable.